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Journal Clubs for 2015

Date (2015) Speaker Topic
02 Feb David  
09 Feb Engela  
16 Feb Mbali  
23 Feb Journal watch  
     
02 Mar George  
09 Mar Fierdoz  
16 Mar Philip  
23 Mar Justine  
30 Mar Journal watch  
     
06 Apr HOLIDAY  
13 Apr Research  
20 Apr CANCELLED  
27 Apr HOLIDAY  
     
04 May Mbali  
11 May Engela  
18 May David  
25 May CANCELLED  
     
01 Jun Joy  
08 Jun Surita  
15 Jun CANCELLED  
22 Jun CANCELLED  
29 Jun George  
     
06 Jul PhD Student  
13 Jul VACATION  
20 Jul Engela  
27 Jul Journal watch  
     
03 Aug Mbali  
10 Aug HOLIDAY  
17 Aug Fierdoz  
24 Aug CANCELLED  
31 Aug Joy  
     
07 Sep Journal watch  
14 Sep Philip  
21 Sep Mbali  
28 Sep Journal watch  
     
05 Oct Journal watch  
12 Oct David  
19 Oct Justine  
26 Oct Journal watch  
     
02 Nov Surita  
09 Nov Journal watch  
16 Nov George  
23 Nov Fierdoz  
30 Nov Journal watch  

 

Journal Clubs for 2014

Date (2014) Speaker Topic
03 Feb Hendre  
10 Feb CANCELLED  
17 Feb CANCELLED  
24 Feb Journal watch  
     
03 Mar David  
10 Mar Mbali  
17 Mar CANCELLED  
24 Mar Dalia  
31 Mar CANCELLED  
     
07 Apr Michelle  
14 Apr Journal watch  
21 Apr HOLIDAY  
28 Apr HOLIDAY  
     
05 May Philip  
12 May Fierdoz  
19 May Joy  
26 May Journal watch  
     
02 Jun George  
09 Jun Journal watch  
16 Jun HOLIDAY  
23 Jun Mbali Apolipoprotein O is mitochondrial and promotes lipotoxicity in heart
Turkieh A, el al.
J Clin Invest. 2014;124(5): 2277-2286
30 Jun Journal watch  
     
07 Jul Michelle  
14 Jul CANCELLED  
21 Jul David Jorgenson AB, Frikke-Schmidt FR, BG Nordestgaard, Tybjaerg-Hanse A.
Loss of function mutations in apolC and risk of ischemic vascular disease
N Engl J Med 2014; 18th June

Kathiresen S, et al.
Loss of function mutations in apoC3, triglycerides and coronary disease
N Engl J Med 2014; 18th June
28 Jul Journal watch  
     
04 Aug Fierdoz  
11 Aug Philip  
18 Aug George  
25 Aug Journal watch  
     
01 Sep CANCELLED  
08 Sep Michelle  
15 Sep Surita Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations. Gammage et al.
EMBO Molecular Medicine Vol 6(4) 2014
22 Sep Engela  
29 Sep Mbali  
     
06 Oct David Cash TP, et al.  Aging cell 2014:1-4.  Exome sequencing of three cases of familial exceptional longevity.
13 Oct Justine  
20 Oct Fierdoz  
27 Oct Journal watch  
     
03 Nov Philip  
10 Nov CANCELLED  
17 Nov  Joy  
24 Nov Journal watch  
     
01 Dec Engela  
08 Dec Mbali  

 

 

Journal Clubs for 2013

Date (2013) Speaker Topic
04 Feb David M Luevano-Contreras C, et al.  Role of dietary advanced glycation end products in diabetes mellitus.
J Evidence-Based Complementary & Alternative Medicine. 2013;18:50-66.
11 Feb Nalene  
18 Feb Chilu  
25 Feb Celeste  
     
04 Mar Mbali Utility and limitations of biochemical markers of vitamin B12 deficiency
Herrmann, W. and Obeid, R. European Journal of Clinical Investigation 2013; 43 (3): 231-237
11 Mar David H Identification of a SIRT1 Mutation in a Family with Type 1 Diabetes
Cell Metabolism:17(3):448-455, 5 March 2013
18 Mar CANCELLED  
25 Mar Hendre Hydrogen sulfide as an oxygen sensor-a mini review
Kenneth R. Olson
Clin Chem Lab Med 2013; 51(3): 623-632 (March issue)
     
01 Apr HOLIDAY  
08 Apr Fierdoz  
15 Apr Philip  
22 Apr Chilu Increased brain uptake and oxidation of acetate in heavy drinkers
Jiang et al.
J Clin Invest 2013; 123(4):1605-1614
29 Apr Celeste  
     
06 May David M  
13 May Mbali Multiplex Immunoassays of Peptide Hormones Extracted from Formalin-Fixed, Paraffin-Embedded Tissue Accurately Subclassify Pituitary Adenomas
Strathmann F.G., et al.
Clin Chem 2012;58(2):366-374
20 May Hendre Vitamin B12 Deficiency
S P Stabler
NEJM 368 (2):149-160 (10 Jan 2013)
(a clinical practice review article)
27 May Surita Exome sequencing reveals a homozygous mutation in TWINKLE as the cause of multisystemic failure including renal tubulopathy in three siblings
Chitra Prasad, Serge B. Melancon, C. Anthony Rupar, Asuri N. Prasad, Laura Dempsey Nunez, David S. Rosenblatt, Jacek Majewski
Molecular Genetics and Metabolism  108 (2013) 190-194
     
03 Jun George  
10 Jun CANCELLED  
17 Jun HOLIDAY  
24 Jun Chilu Muelly et al., Biochemical correlates of neuropsychiatric illness in maple syrup urine disease.
Journal of Clinical Investigation 2013;123(4):1809-1820.
     
01 Jul Fierdoz  
08 Jul Joy FOXO1 impairs whereas statin protects endothelial function in diabetes through reciprocal regulation of Krüppel-like factor 2
Hae-Young Lee et al
National Research Laboratory of Cardiovascular Stem Cell Niche and Dept of Internal Medicine, Seoul National University Hospital
Seoul, Korea
15 Jul VACATION  
22 Jul VACATION  
29 Jul LABMED  
     
05 Aug George  
12 Aug Mbali Time-Dependent Degradation Pattern of Cardiac Troponin T Following Myocardial Infarction
Cardinaels E, et al.
Clin Chem 2013;59:7(1083-1090)
19 Aug CANCELLED  
26 Aug Hendre  
     
02 Sep Philip  
09 Sep David M  
16 Sep Mbali  
23 Sep CANCELLED  
30 Sep Michelle  
     
07 Oct CANCELLED  
14 Oct Fierdoz  
21 Oct Hendre  
28 Oct George  
     
04 Nov CANCELLED  
11 Nov Surita  
18 Nov Michelle  
25 Nov Philip  
     
02 Dec GUEST  

 

 

Journal Clubs for 2012

Date (2012) Speaker Topic
06 Feb David M Oxidized high-density lipoprotein as a risk factor for cardiovascular events in prevalent hemodialysis patients
Hirokazu Hondaa et al
Atherosclerosis 220 (2012) 493– 501
13 Feb John

The Athlete Biological Passport
Sottas P et al
Clin Chem 57:7:969-76 (2011)

20 Feb Nalene Review Article
Update on investigating hypoglycaemia in childhood
Timothy F Lang
Ann Clin Biochem 2011; 48: 200-211. DOI: 10.1258/acb.2011.011012
27 Feb Celeste Diagnostic Potential of Saliva: Current State and Future Applications
Clinical Chemistry May 2011 vol.57 no.5 675-687
     
05 Mar ETHICS: Nada Euthanasia
12 Mar Fierdoz  
19 Mar ETHICS: Lauraine Circumcision
26 Mar CANCELLED  
     
02 Apr Neil Harris Metal Toxicity
09 Apr HOLIDAY  
16 Apr George  
23 Apr Chilu IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in coeliac disease-associated inflammation and lymphomagenesis
Malamut G, Machhour R et al
J Clin Invest 2010; Vol 120(6):2131-2143
30 Apr CANCELLED  
     
07 May David H A PGC1-a-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
Nature 481: 463 (26 January 2012)
14 May ETHICS: Frieda  
21 May Pete

1. Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes Nature 20 July 2010

2. SIRT3 regulates mitochondrial fatty acid oxidation by reversible enzyme deacetylation Nature 4 March 2010

3. (if there's time) Central control of fever and female body temperature by RANKL/RANK Nature 26 November 2009

28 May CANCELLED  
     
04 Jun Philip

Rehfeld, J. F. (2012) Pitfalls in Diagnostic Gastrin Measurements.
Clin Chem 58: 831-836

Rehfeld, J. F. (2011) The Zollinger-Ellison Syndrome and Mismeasurement of Gastrin.
Gastroenterology 140: 144-1453

11 Jun Nalene  
18 Jun David M Infection regulates pro-resolving mediators that lower antibiotic requirements
Chiang N, et al.
Nature 2012;484:524-528
25 Jun CANCELLED  
     
02 Jul Philip Thanatochemistry
Camille Boulagnon, Roselyne Garnote, Paul Fornes and Philippe Gillery
Clin Chem Lab Med 2011;49(8):1265–1270
09 Jul Dr Jialal Diabetes is a pro-inflammatory state: Implications for vascular complications.
16 Jul VACATION  
23 Jul Chilu Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy
Sinha, You et al.
J. Clin. Investigation 2012; vol.122 (7) 2428-2438
30 Jul Celeste  
     
06 Aug Fierdoz  
13 Aug George  
20 Aug David H

Low Circulating Adropin Concentrations with Obesity and Aging Correlate with Risk Factors for Metabolic Disease and Increase after Gastric Bypass Surgery in Humans
J Clin Endocrinol Metab, October 2012, 97(10)

Detecting growth hormone abuse in athletes
Anal Bioanal Chem (2011) 401:449–462

27 Aug Celeste  
     
03 Sep Mbali Inappropriate Requesting of Glycated Haemoglobin (HbA1c) is widespread.
Drickell OJ, Holland D, Hanna FW, et al.
Clin Chem 2012;58(5)906-915
10 Sep Chilu  
17 Sep David M  
24 Sep HOLIDAY  
     
01 Oct PATH CONGRESS  
08 Oct Mbali Diagnostic utility of osteocalcin, undercarboxylated osteocalcin and alkaline phosphatase for osteoporosis in premenopausal and postmenopausal women
Annals of Laboratory Medicine 2012;32:23-30
Atalay S, et al
15 Oct David M Structural basis of Wolman Disease and cholesteryl ester storage disease.
Saito S, et al.
Mol Gen Metab 2012;105:244-248.
22 Oct Fierdoz  
29 Oct Ryan A polemic on stochastic processes in clinical chemistry
     
05 Nov Philip Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
Talukdar et al.
Nature Medicine (2012) 18:1407-1414
12 Nov SYMPOSIUM  
19 Nov George  
26 Nov David H

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
Nature 2012 Sep 13;489(7415):318-21

Fasting time and lipid levels in a community-based population
Arch Intern Med. Published online November 12, 2012

     
3 Dec Surita